The STIRENA project focused on the development of novel stimuli-responsive nanoparticles for potential applications as drug delivery

2011-06-11

Physical stimuli-responsive vesicles in drug delivery: Beyond liposomes and polymersomes Cubosomes: The Next Generation of Smart Lipid Nanoparticles? Avhandlingar om THERMO-RESPONSIVE POLYMERS. Inorganic and organic polymer-grafted nanoparticles : their nanocomposites and characterization. W. Zhao et al., "In Situ Cross-Linking of Stimuli-Responsive "Combination of silica nanoparticles with hydroxyapatite reinforces poly (L-lactide In his thesis, Daniel Klinger highlights the approach of stimuli-responsive microgels for such applications and discusses why especially light as a trigger has an av L Carlsson · 2014 · Citerat av 55 — The nanoparticles were found to increase in size with increasing molar mass of properties such as hydrophobicity or responsiveness to external stimuli. as this polymer is both thermo- and pH-responsive, which makes it Characterization of modified mesoporous silica nanoparticles as vectors for Stimuli-responsive hybrid nanocarriers developed by controllable integration of av H Zhang · 2020 · Citerat av 1 — Neither open-loop nor closed-loop stimuli affected natural gait significantly, Walking speed is a responsive measure of functional status and overall health [1]. crystalline nanoparticles responsive to fungal lipases: A potential platform for Oren Regev, Luciano Galantini; Multi Stimuli Response of a Single Surfactant "Peptide Functionalized Gold Nanoparticles as a Stimuli Responsive Contrast Medium in Multiphoton Microscopy." Nano Lett 17, no. 3 (Mar 08 nanofabrication; localized surface plasmon resonance; alloy nanoparticles; of optical and electrical pH sensors based on stimuli-responsive hydrogels.

Stimuli responsive nanoparticles

Such systems are able to control drug release by reacting to naturally occurring or external applied stimuli. Special attention is paid to the design and nanoparticle formulation of these so‐called smart drug‐delivery systems. Syntheses of nanoparticles with simultaneous or sequential responses to two or more stimuli (pH-redox, pH-light, redox-light, temperature-magnetic, pH-redox-temperature, redox-enzyme-light, etc.) and the applications of such responsivity properties for drugs control and release have become a hot topic of recent research. Taking this into account, stimuli responsive nanoparticles present the ability to enhance therapeutic efficacy and reduce side effects.

Biomimetiska material genom molekylär prägling. Polymer nanoparticles with pre-defined molecular recognition and stimuli-responsive properties are very

In this review we provide an analysis of recent literature reports on the synthesis and applications of stimuli-responsive polymeric and hybrid nanostructured particles in a range of sizes from nanometers to a few micrometers: nano- and microgels, core–shell structures, polymerosomes, block-copolymer micelles, and more complex architectures. There is increasing evidence that stimuli‐responsive nanomaterials have become significantly critical components of modern materials design and technological developments. Recent advances in synthesis and fabrication of stimuli‐responsive polymeric nanoparticles with built‐in stimuli‐responsive components (Part A) and surface modifications of functional nanoparticles that facilitate responsiveness (Part B) are outlined here.

I am currently working in a project on stimuli-responsive drug delivery vehicles. These lipid nanoparticle carriers, liposomes, can be induced to release the drug

PGR-P-352. Key facts Type of research degree PhD Application deadline Ongoing deadline Country eligibility International (open to all nationalities, including the UK) Funding Competition funded 2019-09-16 The present disclosure provides stimuli-responsive magnetic nanoparticles, methods of making the magnetic nano-particles, and methods of using the magnetic nanoparticles. The magnetic nanoparticles include a metal oxide core; and a shell that includes a stimuli-responsive polymer having a terminal group that directly coordinates to the metal oxide core. Abstract. Stimuli-responsive polymeric nanoparticles have recently gained tremendous attention, in particular in the field of controlled drug delivery as a result … T D ACCEPTED MANUSCRIPT Dual stimuli-responsive polypyrrole nanoparticles for anticancer therapy Rania M. Hathout 1, AbdelKader A. Metwally 1, Sherweit H. El-Ahmady 2, Eman S. Metwally 3, Noha A. Ghonim 3, Salma A. Bayoumy 3, Tarek Erfan 3, Rosaline Ashraf 3, Maha Fadel 4, Abdullah I. El-Kholy 4 and John G. Hardy 5,6 1 Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy 2011-06-11 This class of stimuli-responsive nanoparticles is inactive during blood circulation and under normal physiological conditions, but is activated by acidic pH, enzymatic up-regulation, or hypoxia once they extravasate into the tumor microenvironment.

Special attention is paid to the design and nanoparticle formulation of these so‐called smart drug‐delivery systems. Stimuli-responsive nanoparticles have been designed and studied, exploring their potentiality as self-assembled materials as building blocks for the development of "smart" materials for bio-applications. Perylene diimide derivatives (PDI) have been used as fluorogenic units and structural components of assembled high-brightness nanoparticles, where fluorescence changes can be triggered by Dual stimuli‐responsive nanoparticles capable of fine‐tuning drug release to augment therapeutic efficacy have become a promising tool for anticancer drug delivery. However, the rational design of these “smart” nanoparticles for a selective delivery and controlled release of multidrug combinations in cancer cells to achieve synergistic effects remain challenging. 2016-01-07 Stimuli-responsive nanoparticles would provide a universally applicable platform, with the cargoes playing important roles for MDR reversion.
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Author information: (1)Donostia International Physics Center (DIPC), Manuel de Lardizabal 4, 20018 Donostia-San Sebastián, Spain. marek.grzelczak@dipc.org. Taking this into account, stimuli responsive nanoparticles present the ability to enhance therapeutic efficacy and reduce side effects.

To address the issue of tumor heterogeneity, neoantigens of specific tumors are required for screening for personalized therapy. Stimuli-responsive polymeric nanomaterials for rheumatoid arthritis therapy Abstract. Rheumatoid arthritis (RA) is a long-term inflammatory disease derived from an autoimmune disorder of the INTRODUCTION. Rheumatoid arthritis (RA) is a long-term inflammatory disease derived from an autoimmune
The devil will find work for idle hands to do

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